Inflammation
Low Dose Naltrexone (LDN): A Novel Approach to Chronic Pain, Inflammation, and Recovery
Naltrexone is a medication that has been used for decades at higher doses, typically 50 mg, for the treatment of opioid and alcohol use disorders. At these doses, it works by blocking opioid receptors, which reduces the reinforcing effects of addictive substances. Low dose naltrexone, usually defined as doses between 0.5 mg and 4.5 mg, works very differently. Instead of sustained opioid blockade, it produces a brief and partial receptor blockade that appears to trigger downstream regulatory effects in the nervous system and immune system.
Avoiding Cryotherapy is Beneficial in the Treatment of Many Musculoskeletal Injuries
For decades, ice packs were a cornerstone of injury management. Coaches and clinicians routinely prescribed “RICE” (Rest, Ice, Compression, Elevation) for everything from sprains to muscle soreness. But in recent years, our understanding of muscle physiology and tissue repair has evolved, and so has our use of cryotherapy.
How Blood Sugar Damages Tendons: The Hidden Role of AGEs
Tendons are resilient structures, built to transmit force from muscle to bone. But like other tissues in the body, they are vulnerable to the damaging effects of elevated blood sugar. One of the most important biochemical contributors to tendon degeneration in metabolic disease is the formation of advanced glycation end products, or AGEs.