PRP
Comparing Biological Therapies for the Treatment of Knee Osteoarthritis
Knee osteoarthritis (OA) is a degenerative joint disease that leads to cartilage loss, pain, stiffness, and functional decline. While joint replacement remains a final option for severe cases, many patients seek less invasive solutions that can relieve symptoms and delay or prevent surgery. Regenerative and orthobiologic therapies have emerged as promising options, offering tissue-supportive and anti-inflammatory effects. This article compares four common injectable treatments, hyaluronic acid (HA), platelet-rich plasma (PRP), microfragmented adipose tissue (MFAT), and bone marrow aspirate concentrate (BMAC), in the management of knee OA.