Regenerative Medicine
Phimosis: A Non-Surgical Approach to Promote Retraction and Restore Function
Phimosis is a condition in which the foreskin cannot be fully retracted over the glans penis. While this is common in children and typically resolves naturally by adolescence, in adults it can cause pain with erections, hygiene problems, and recurring inflammation. In more severe cases, phimosis may progress to paraphimosis, a urologic emergency where the retracted foreskin becomes stuck behind the glans, restricting blood flow and risking permanent injury.
Modern Tendinopathy Treatment: Beyond Rest and Injections
Tendinopathy is a degenerative condition of tendon tissue that impairs function and often resists standard treatment. Tendinopathy can be broadly divided into two categories: tendinitis which is the early onset of tendon injury, and tendinosis which is a chronic, painful, degenerative state. Traditionally, management involved rest, NSAIDs, corticosteroid injections, or even surgical debridement. But modern research has shown that these strategies often miss the underlying problem: tendinopathy is not primarily an inflammatory condition, but a failed healing response driven by mechanical and molecular dysregulation.
Muscle Fibrosis and Aging: Why Strength Fades and What Can Be Done
As we age, many people assume that weakness and muscle loss are inevitable. While some decline in strength is expected, much of what we attribute to “aging” is actually due to specific biological processes, particularly muscle fibrosis. Unlike muscle atrophy alone, fibrosis involves a shift in tissue architecture, replacing healthy muscle fibers with stiff, disorganized collagen. This change reduces mobility, strength, and responsiveness to exercise.
TriMix Therapy: A Temporary Tool for Long-Term Erectile Function
Erectile dysfunction (ED) is a multifactorial condition that can result from hormonal imbalance, vascular insufficiency, nerve injury, or chronic illness. While many patients respond to first-line oral medications like tadalafil or sildenafil, others require more direct interventions. TriMix, an intracavernosal injection therapy, is a powerful short-term solution used in select cases. At the Performance Medicine Institute, we view TriMix not as a lifelong therapy, but as a transitional tool, one used to restore penile tissue responsiveness while working to correct the underlying causes of ED.
Comparing Biological Therapies for the Treatment of Knee Osteoarthritis
Knee osteoarthritis (OA) is a degenerative joint disease that leads to cartilage loss, pain, stiffness, and functional decline. While joint replacement remains a final option for severe cases, many patients seek less invasive solutions that can relieve symptoms and delay or prevent surgery. Regenerative and orthobiologic therapies have emerged as promising options, offering tissue-supportive and anti-inflammatory effects. This article compares four common injectable treatments, hyaluronic acid (HA), platelet-rich plasma (PRP), microfragmented adipose tissue (MFAT), and bone marrow aspirate concentrate (BMAC), in the management of knee OA.
Innovative Treatment for Hard Flaccid Syndrome: A Multimodal, Regenerative Approach
Hard flaccid syndrome is a distressing and poorly understood condition that primarily affects men between the ages of 20 and 40. It is characterized by persistent penile discomfort, a semi-rigid flaccid state, perineal tension, and erectile dysfunction that cannot be attributed to typical organic or psychological causes alone. Because it overlaps with both pelvic floor dysfunction and neurovascular dysregulation, treatment requires a nuanced, multidisciplinary approach. At the Performance Medicine Institute, we combine pelvic rehabilitation with regenerative therapies and metabolic support to offer a comprehensive strategy for recovery.