Testosterone Therapy
Testosterone Replacement Therapy Shows a Favorable Cardiovascular and Systemic Safety Profile When Properly Prescribed
Testosterone replacement therapy, often shortened to TRT, is one of the most discussed treatments in men’s health.
Optimizing Health and Performance in Klinefelter Syndrome: Testosterone, Fertility, Metabolic Health, and Long-Term Wellness
Klinefelter syndrome is a genetic condition that affects males and is most commonly caused by an extra X chromosome. The classic chromosome pattern is 47, XXY, although some patients have mosaic patterns or other variations.
Optimizing Fertility on Testosterone Therapy: Maintaining Testicular Function, Size and Sperm Production
Testosterone therapy can be life-changing for men with symptomatic testosterone deficiency. It can improve energy, mood, libido, sexual function, body composition, training response, and overall quality of life when used appropriately. However, testosterone therapy also changes the normal hormonal signaling between the brain and the testes.
Labs to Check for Testosterone Replacement Therapy
Testosterone replacement therapy (TRT) is only as good as the monitoring behind it. Symptoms matter, but labs are what let us confirm dose adequacy, reduce side effects, and identify cardiometabolic risk factors that often coexist with low testosterone.
TRT Delivery Options: Intramuscular Injections, Subcutaneous Injections, Pellets and Topical Creams
Testosterone replacement therapy (TRT) can work very well, but the delivery method matters more than most people expect. The same dose can feel very different depending on how steadily it is absorbed, how high the peaks run after dosing, how low levels fall before the next dose, and how consistent day to day exposure is.
Sarcopenia: Understanding and Reversing Age-Related Muscle Loss
Sarcopenia is the progressive loss of skeletal muscle mass, strength, and function associated with aging. While some degree of muscle decline is expected with age, sarcopenia reflects a pathologic process that accelerates physical disability, increases the risk of falls, and contributes to frailty and loss of independence. It often begins subtly in the fourth decade of life and progresses more rapidly after age 60, particularly in sedentary individuals or those with chronic illness.
TriMix Therapy: A Temporary Tool for Long-Term Erectile Function
Erectile dysfunction (ED) is a multifactorial condition that can result from hormonal imbalance, vascular insufficiency, nerve injury, or chronic illness. While many patients respond to first-line oral medications like tadalafil or sildenafil, others require more direct interventions. TriMix, an intracavernosal injection therapy, is a powerful short-term solution used in select cases. At the Performance Medicine Institute, we view TriMix not as a lifelong therapy, but as a transitional tool, one used to restore penile tissue responsiveness while working to correct the underlying causes of ED.
Testosterone Therapy for Women: A Critical Hormone for Energy, Libido, and Wellbeing
While testosterone is typically associated with men’s health, it also plays a critical role in the wellbeing of women. Produced in the ovaries and adrenal glands, testosterone contributes to libido, energy, muscle mass, bone density, and mood regulation. For many women, especially those approaching menopause or who have undergone surgical oophorectomy, testosterone levels decline significantly which leads to a constellation of symptoms that can be addressed with carefully monitored hormone replacement therapy.
Optimizing long-term health in patients with HIV
Modern HIV treatment has transformed HIV from a life-threatening infection into a chronic, manageable medical condition for many people. Antiretroviral therapy, or ART, is one of the great success stories in modern medicine. For people living with HIV, staying on effective ART is essential for viral suppression, immune protection, long-term health, and prevention of transmission.